The emergence of the field of adolescent and young adult (AYA) oncology was led by analyses of the epidemiology of cancer occurring across a span of ages from childhood to older adulthood. Trends demonstrated multiple unique aspects that defined the population to be studied as those diagnosed at ages 15-39, including differences in the incidence of various cancers among AYAs and varied rates of survival outcomes. Further study has demonstrated that differences in the underlying biology of cancers that occur in the AYA age range can explain many of these trends. In this session, we will review the epidemiology of AYA cancer and the unique biology associated with cancers diagnosed in the AYA age range.
Landmark Articles
- CA A Cancer J Clinicians – 2020 – Miller – Cancer statistics for adolescents and young adults 2020
- Cancer – 2016 – Tricoli – Biologic and clinical characteristics of adolescent and young adult cancers: acute lymphoblastic leukemia, colorectal, breast, melanoma, and sarcoma
- Cancer – 2017 – Tricoli – A mutational comparison of adult and adolescent and young adult (AYA) colon cancer
- Hematology – 2018 – Roberts – Genetics and prognosis of ALL in children vs adults
- Intl Journal of Cancer – 2018 – Wilmott – Whole genome sequencing of melanomas in adolescent and young adults reveals
- JAMA – 2020 – Scott – Trends in cancer incidence in US adolescents and yound adults, 1973-2015
- JNCCN – 2013 – Tichy – Breast cancer in adolescents and young adults: a review with a focus on biology
